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\u4ed6\u4eec\uff0c\u5e38\u88ab\u79f0\u4e3a\u81ea\u95ed\u75c7\u8005\uff08Autism\uff09\uff0c\u4e5f\u88ab\u53eb\u4f5c\u5b64\u72ec\u75c7\u513f\u3002<\/p>\n

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1. \u795e\u7ecf\u751f\u7269\u5b66\u7814\u7a76\u53d1\u73b0\uff0c\u5b64\u72ec\u75c7\u75c5\u513f\u4e2d\u5b58\u5728\u795e\u7ecf\u9012\u8d28\u7684\u5f02\u5e38\uff0c\u795e\u7ecf\u7ec6\u80de\u8fc1\u79fb\u7684\u5f02\u5e38\u3002\u901a\u8fc7\u6b63\u7535\u5b50\u53d1\u5c04\u4f53\u5c42\u6444\u5f71\uff08PET\uff09\u3001\u529f\u80fd\u6027\u6838\u78c1\u5171\u632f\u6210\u50cf\uff08fMRI\uff09\u4ee5\u53ca\u5355\u5149 \u5b50\u53d1\u5c04\u7535\u5b50\u8ba1\u7b97\u673a\u4f53\u5c42\u626b\u63cf\uff08SPECT\uff09\uff0c\u53d1\u73b0\u5b64\u72ec\u75c7\u7684\u8fb9\u7f18\u7cfb\u7edf\u3001\u8111\u5e72\u548c\u5c0f\u8111\u4ee5\u53ca\u76f8\u5173\u76ae\u5c42\u5b58\u5728\u7ed3\u6784\u548c\u4ee3\u8c22\u65b9\u9762\u7684\u5f02\u5e38\uff0c\u8111\u5e72\u3001\u6d77\u9a6c\u3001\u80fc\u80dd\u4f53\u7b49\u4e5f\u6709\u5f02\u5e38\u3002<\/p>\n

2.\u5fc3\u7406\u5b66\u7814\u7a76\u8ba4\u4e3a\u5b64\u72ec\u75c7\u7684\u6838\u5fc3\u75c5\u56e0\u662f\u7531\u4e8e\u6267\u884c\u529f\u80fd\u7684\u7f3a\u635f\u3002<\/p>\n

3.\u514d\u75ab\u5b66\u4e13\u5bb6\u4eec\u7814\u7a76\u53d1\u73b0\u514d\u75ab\u548c\u611f\u67d3\u56e0\u7d20\u5728\u5b64\u72ec\u75c7\u75c5\u56e0\u4e2d\u53d1\u6325\u4e86\u91cd\u8981\u7684\u4f5c\u7528\uff0c\u5148\u5929\u6027\u98ce\u75b9\u75c5\u6bd2\u611f\u67d3\u3001\u5de8\u7ec6\u80de\u75c5\u6bd2\u611f\u67d3\u88ab\u8ba4\u4e3a\u53ef\u80fd\u4e0e\u5b64\u72ec\u75c7\u53d1\u75c5\u6709\u5173\u3002\u800c\u4e14\u7531\u4e8e\u5728\u5b64\u72ec\u75c7\u513f\u7ae5T\u6dcb\u5df4\u7ec6\u80de\u4e9a\u7fa4\u4e5f\u4e0e\u6b63\u5e38\u4eba\u7fa4\u6709\u5dee\u522b\uff0c\u63d0\u793a\u5b64\u72ec\u75c7\u4e0e\u514d\u75ab\u7cfb\u7edf\u5f02\u5e38\u6709\u5173\u3002<\/p>\n

4.\u9057\u4f20\u5b66\u5bb6\u4eec\u53d1\u73b0\u7b2c16\u53f7\u67d3\u8272\u4f53\u7684\u5fae\u5220\u9664\uff08microdeletion\uff09\u662f\u81ea\u95ed\u75c7\u7684\u9ad8\u5ea6\u98ce\u9669\u56e0\u5b50\uff0c\u540c\u65f6\u8fd8\u8ba4\u4e3a5\u53f7\u67d3\u8272\u4f53\u572815%\u7684\u5b64\u72ec\u75c7\u6210\u56e0\u4e0a\u8d77\u7740\u5173\u952e\u4f5c\u7528(\u6b64\u7814\u7a76\u66fe\u83b7\u300a\u65f6\u4ee3\u300b\u8bc4\u51fa2009\u5e74\u5341\u5927\u533b\u5b66\u7a81\u7834\uff09\u3002<\/p>\n

5.\u4e34\u5e8a\u5b66\u8005\u4eec\u901a\u8fc7\u5927\u6837\u672c\u7edf\u8ba1\u5b66\u5206\u6790\u8fd8\u53d1\u73b0\u51fa\u751f\u4f53\u91cd\u663e\u7740\u5c0f\u4e8e\u548c\u5927\u4e8e\u80ce\u9f84\u513f\u7684\u81ea\u95ed\u75c7\u98ce\u9669\u589e\u52a0\u660e\u663e\uff0c\u6bcd\u4f53\u7cd6\u5c3f\u75c5\u548c\u80a5\u80d6\u75c7\u4e5f\u5f88\u6709\u53ef\u80fd\u5bfc\u81f4\u513f\u7ae5\u60a3\u4e0a\u5b64\u72ec\u75c7\u6216\u5176\u5b83\u53d1\u80b2\u969c\u788d\u75be\u75c5\u3002<\/p>\n

\u5f53 \u7136\uff0c\u66f4\u591a\u7684\u6210\u679c\u8fd8\u5728\u4e0d\u65ad\u7684\u6d8c\u73b0\uff1a\u300aEpidemiology\u300b\u6742\u5fd7\u7814\u7a76\u6307\u51fa\uff0c\u5b55\u5987\u9002\u5f53\u8865\u5145\u7ef4\u751f\u7d20\u53ef\u964d\u4f4e\u5b69\u5b50\u60a3\u81ea\u95ed\u75c7\u98ce\u9669\uff1b\u300aCurrent Biology\u300b\u7814\u7a76\u8868\u660e\u5bf9\u5a74\u513f\u6d4b\u91cf\u8111\u7535\u6ce2\u53d8\u5316\u60c5\u51b5\u5c31\u80fd\u9884\u77e5\u60a3\u5b64\u72ec\u75c7\u7684\u98ce\u9669\uff1b\u300aThe Archives of General Psychiatry\u300b\u79d1\u5b66\u5bb6\u53d1\u73b0\u81ea\u95ed\u75c7\u60a3\u8005\u5927\u8111\u4e2d\u4e59\u9170\u80c6\u78b1\u7684\u542b\u91cf\u4f4e\u4e8e\u6b63\u5e38\uff1b\u300aJournal Of Autism and Developmental Disorders\u300b\u7814\u7a76\u8005\u5219\u8868\u793a\u6559\u5b64\u72ec\u75c7\u513f\u7ae5\u6a21\u4eff\u80fd\u529b\u53ef\u6539\u5584\u5176\u793e\u4ea4\u6280\u80fd\uff1b\u300aCell\u300b\u6742\u5fd7\u627e\u5bfb\u51fa\u4e86\u5b64\u72ec\u75c7\u9057\u4f20\u4e0a\u7684\u7a81\u53d8\u70ed\u70b9\uff1b\u300aNature\u300b\u6742\u5fd7\u4e0a\u53d1\u73b0 \u4e86\u591a\u4e2a\u4e0e\u81ea\u95ed\u75c7\u76f8\u5173\u7684\u65b0\u57fa\u56e0\u3002<\/p>\n

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